On October, 6, 2015, Li Yuanyue, PhD student of School of Life Sciences, Xiamen University published a paper on Nature Methods entitled “Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files”.

　　Discovery proteomics has limited quantification capabilities because of stochastic precursor-ion selection. Several data-independent acquisition (DIA) methods have been proposed to overcome this limitation, including the sequential-window acquisition of all theoretical mass spectra (SWATH-MS).

        The research team developed a SWATH data-processing software named Group-DIA, which is working as well as DIA-Umpire, while 30-50% better in stochastic precursor-ion. This software could promote the application of SWATH-MS to bio-research and offer a good approach for future studies.

         Li Yuanyue, PhD student and Zhong Chuanqi, post-PhD candidate in the research team led by Prof. Han Jiahuai undertake the major research work.

          Articl Website： www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.3593.html